Download All Heal. A Medical and Social Miscellany by R. M. Shaw, R. A. Bowen, G. E. Paget PDF

By R. M. Shaw, R. A. Bowen, G. E. Paget

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Extra resources for All Heal. A Medical and Social Miscellany

Sample text

The Fascination of Hormone Therapy Hormonal control of cancer is the most exciting event in the realm of tumour biology. The concept that cancer is an irreversible state, D 42 SIR STANFORD CADE independent and uncontrollable, is obviously no longer true. It can be controlled by physiological means ; it is dependent on normal phenomena; it relies on its environment for survival. This concept of hormone dependence has led to an entirely new method of treatment. To the time-honoured methods of treatment—'cut it out', 'burn it out', 'poison it', methods which aimed at the direct attack on cancer with the object of destroying it—has been added an indirect attack, the weapon of physiological warfare against cancer.

There will be a lessened facility in the choosing of words, the available vocabulary remaining intact. The number of 'types'—that is different words employed—is reduced. Less common terms are selected slowly, if at all, and with a notable inconsistency. Defect of word-finding is revealed when the patient tries to recite a catalogue of instances belonging to a particular generic class (animals, flowers) ; or sharing a common property (redness, sharpness). Pari passu with the restriction of vocabulary in actual use is an over-employment of certain trite phrases and phrase-words, clichés, preformed speech-patterns, favoured word-linkages, verbal biases, and successive habits of connected speech.

Bone-marrow depletion, haematopoietic depression, undesirable side-effects on mucous membranes, severe gastrointestinal upsets, are some of the side-effects which occur if the dosage used is to result in tumour regression. Many of the cytotoxic agents are chemically unstable and are excreted or detoxicated rapidly. To ensure an effective concentration of the active drug in the tumour and yet minimize the general undesirable effects, new techniques have been developed. The perfusion of limbs or organs permits the administration locally of doses which would be lethal if they were to reach the general circulation.

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